Is ovarian stimulation painful?

4 fertility expert(s) answered this question

Answer from: Patricio Calamera, MD, MSc, ObGyn

Gynaecologist, Specialist in Reproductive Medicine

Ovarian stimulation shouldn’t be painful. It might be a little uncomfortable during the last days of the protocol because the ovaries are going to be a a little bit bigger, but that is good as it shows us that the patient is actually responding to the IVF protocol and that there will be a lot of oocytes in the oocyte retrieval. So it is a little bit discomfortable but not painful. Another point, during the oocyte pickup, patients are sedated, they don’t feel anything therefore it shouldn’t have to be painful at all.

Answer from: Valentina Denisova, MD PhD Obstetrician Gynaecologist

Gynaecologist, Fertility Specialist
Next Generation Clinic

This is a very frequent question. It will depend on the ovarian reserve. Actually, if a person has normal ovarian reserve during the day of ovarian stimulation she will not feel anything strange inside her body. But when the follicles become bigger and the ovaries become larger, of course, she can feel some discomfort inside her abdomen. So, this is not pain, this is just discomfort and after an ovarian puncture you can feel some pain but in most patients on the evening of the day of the ovarian puncture, there are no problems.

Answer from: Guillermo Quea Campos

Gynaecologist, Specialist in Reproductive Medicine
Pronatal Fertility Clinics

No, ovarian stimulation is not painful. Possibly towards the end of stimulation the patient may feel some discomfort such as pressure on the pelvic or swelling. But the procedure is safe for patients.

Answer from: Scott Nelson, Professor

Gynaecologist, Muirhead Professor of Obstetrics and Gynaecology at Glasgow Royal Fertility Clinic and Medical Director at Access Fertility

The needles that we use are very similar and the pumps that we use are identical to those that type 1 diabetics use every day. You can imagine how many of us will know some type 1 diabetes who injects those insulin four times a day. They’ll be able to tell you that yeah it can be uncomfortable and be sore and you might get some local irritation depending where that site is. Generally, that’s relatively perceived as minor because of how fine those needles are. What you can then also get is kind of just that feeling of fullness because as your ovaries develop and respond to the drugs, you’ve got that sort of pelvic awareness of that and again some can be to some degree with the discomfort there. Most people wouldn’t say though it’s pain as such and if it is, if you are having pain you should contact your clinical team to make sure there’s nothing going wrong.

About this question:

May I expect a pain during or after ovarian stimulation process?

Stimulation is treatment used in assisted reproduction to induce ovulation and increase and mature greater number of oocytes in one ovulation. The process is done with medication or with injection.



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