Answer from: Maria José Mendiola, MD, MSc in Human Genetics, MSc in Science Communication, ObGyn
Autosomal inheritance of a genes means that the gene is located on one of the autosomes and this means that males and females are equally likely to inherit the gene dominant means that a single copy of the gene gives a particular trait, for example, such as brown eyes instead of green eyes when a parent has a dominant gene, there is 50 chance that any child they have will also have the trait.
Answer from: Douglas Lester, PhD, MSc, BSc (Hons)
If you’ve got an autosomal dominant mutation, it means that 50% of your offspring will, on average, be affected. You’ve got a 50/50 chance of passing the bad chromosome or the good chromosome. You’re much more likely to see that that has run in the family. As I said before, if it’s male infertility, you would have to go down the female line and vice versa.
Answer from: Glykeria Samolada, Biologisst, MSc. Mol. Cytogenetics
Autosomal dominant describes the way some genetic changes are or can be inherited. Autosomal means the change is in an autosome chromosomes 1-22 or to a non-sex chromosome dominant means that the features or symptoms can be observed when a single copy of its chromosomes or gene is affected. You need only one mutated gene to be affected by this type of disorder. A person with an autosomal dominant disorder, let’s say the father, has a 50% chance of having an affected child with one mutated, gene dominant team and a 50% chance of having an unaffected child with two normal gene recessivity. Achondroplasia and Huntington disease are examples of autosomal dominant disorder.
