How can PGT-A reduce the time to pregnancy?
Does the PGT-A shorten the time to pregnancy?
Preimplantation Genetic Testing for Aneuploidy (PGT-A) is a tool for selecting euploid (normal) embryos and can help to choose embryos more likely to result in a successful pregnancy.
The PGT-A does not allow us to modify anything in the embryo because we cannot fix the genetic problems of the embryos. However, it can significantly reduce the time needed to achieve pregnancy. The main reason is that, especially in cases of patients who produce a lot of embryos but have a low percentage of normal embryos, we discard many embryos that could have been transferred based solely on their morphological quality.
For instance, if we consider that patients over 40 may have as low as a 10% or 15% chance of having normal embryos, a patient with 6 to 10 embryos may have to undergo several rounds of negative transfers until a normal one is transferred. By performing PGT-A, we discard all abnormal embryos, focusing only on transferring those that can potentially result in healthy babies.
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