Answer from: Raúl Olivares, MD
No, if you miss one day of progesterone, especially if you have had an IVF or an IUI is never an issue because your ovaries are going to produce your own progesterone. In other cases, for example, if you’re having a cryotransfer, and you are under a hormone replacement treatment or if you are going through an egg donation, and you are also on hormonal replacement therapy, I would say it’s not an issue. The reason is that the progesterone can keep the levels for some time, and I’ve got cases in which patients thought that they had a miscarriage, they have stopped the treatment even for five or six days, and when they have come, and we have done the scan there was an embryo with a heartbeat they are resuming the treatment and nothing abnormal has happened. Probably, if you just missed one day, there’s not going to be a problem, and the pregnancy is going to go perfectly.
There are cases in which patients also ask that when they are not sure if they are taking the progesterone or sometimes, they have a really important leakage of progesterone, and they are not sure if the pessary has remained inside the vagina or not. They ask us if they can take another progesterone pessary. The only thing I can say is that in regard to progesterone, it’s better to have more than less of it. Whenever you have any doubt that the pessary has been properly placed inside a vagina, or you may have lost a lot of progesterone, take another one, and that’s it, it’s a completely safe procedure.
What should I do if I miss a day or two of progesterone during my IVF cycle?
What happens when you stop taking progesterone after IVF? What if I forget to take my progesterone pill? Will it cause any issues? How long does it take for progesterone pills to work?