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Is there currently any research underway in to why miscarriage happens?

2 fertility expert(s) answered this question

Are there any studies looking for explaining mechanisms behind miscarriage?

Are there any proper studies conducted to explain reasons behind the miscarriage? Are only recurrent miscarriages being studied or also other types? Where to look for information regarding latest discoveries?

Answer from:
Gynaecologist, Subspecialist in Reproductive Medicine, CEO & Founder, NOW-fertility
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There is lots of research in the causes of miscarriage. This is a very dynamic and evolving field. Most of the research in the past has been focusing on thrombophilia (so blood clots) and uterine abnormalities as cause of miscarriage, presence of adhesions inside the uterus, the presence of the uterine septum inside the uterus and also research has been focusing on immune causes of miscarriage. I think what we know now that there are additional factors causing miscarriage such as the male component. So there is some research looking at the causes of miscarriage coming from the male and also what we we know that there are some miscarriages that are still unknown only because not all the available tests implementing routine clinical practice. So there is a growing evidence that some thyroid diseases could be contributing to miscarriage and there are studies looking at the relationship between thyroid disease and pregnancy loss.

Answer from:
Gynaecologist, Consultant Gynaecologist and Sub-Specialist in Reproductive Medicine
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There’s lots of research underway into why miscarriage happens. I think it’s a really exciting area of research. There are groups looking to see whether the immune system is associated with miscarriage – there are several large trials undergoing underway. At the moment there’s a trial called the CERM trial looking to see if chronic endometritis or low-level inflammation in the womb can be treated and whether that reduces the miscarriage rate. So, yes – there are lots of ongoing studies and they can often be accessed through your early pregnancy assessment unit.

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