Answer from: Patricio Calamera, MD, MSc, ObGyn
Not that much. The most important is that you use less medication so the cost of the medication would be the one that you’re going to save but the work in the laboratory which is the most important part of the cost of IVF it’s still done because the biologists have to inject the oocytes with the sperm and culture the embryo with the culture media and everything. So, basically what you save is the cost of the medication.
Answer from: Tomas Frgala, PhD
The disadvantage to drawback might be a lower number of eggs obtained but it’s usually cheaper so, it’s more cost effective for the couple – that’s in many many cases the number one preference or the reason why the patients opt for the Mini IVF but there are some cases or even groups of patients such as patients in higher age and the poor responders where let’s say during the classic stimulation we only get less than six eggs and in that case the Minimal stimulation might actually be preferable. Once again the number of eggs obtained is a little lower but still it might give us a good chance for success at a lower cost overall.
Answer from: Malini Uppal, MBBS, DGO Diploma Prenatal Genetics and Foetal Medicine
The only difference in mild, mini or conventional IVF is the cost of the medication. If you are doing conventional IVF, we are doing full stimulation, you might be someone who requires full stimulation or you might be someone who does not require that amount of medication anyway. You might be dealing with someone who has a good reserve and needs only a very little amount of medication to produce a good number of follicles. I do not think that choosing mild IVF for the cost, should be your reason because overall, if you see the larger picture, you are paying the same amount of money, whether you collect one egg, four eggs or ten eggs.
It depends on what your ovarian reserve is, what your situation is. I don’t think one treatment can benefit or suit all, it has to be individualised, for yourself, for your case, for whatever is the best option for you. Yes, you do save slightly on the amount of medication, however if you are somebody who could get 10 to 12 eggs in a cycle but we gave you milder medication, we end up collecting 4 or 5 and we did not get the outcome of the cycle and means that we have to repeat the cycle. This means you will end up paying double the amount in comparison to if we did achieve those 10, 12 or 13 eggs in one cycle. If you are someone who could produce that many you might end up having some frozen embryos which you can subsequently use and you don’t have to go through a whole stimulation cycle again.
It is a myth that mild stimulation is cheaper, but it depends on the individual, what kind of treatment is best suited, what kind of stimulation is best suited for you and that should be chosen.
Are minimal stimulation IVFs considered as the cheaper option of IVF?
Nowadays patients not only are concerned about costs of treatment but also about the effect of drugs used during the stimulation process. Studies confirmed that higher dosage is not necessarily as effective in case of patients with low or diminished ovarian. Similar case is with PCO patients. What and who can benefit from Mini IVF or Natural Cycle IVF?