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What is embryo aneuploidy?

2 fertility expert(s) answered this question

Answer from: Andrea Sánchez Freire

Senior Embryologist
ReproMed Ireland

Aneuploidy is the presence of an abnormal number of chromosomes. One or more chromosomes can be duplicated or missing in those embryos. Aneuploid embryos can lead to increased rates of miscarriages, birth defects and IVF failure. Studies confirm that the risk of aneuploid embryos increases with maternal age. Preimplantation genetic testing for aneuploidy (PGT-A) studies the number of chromosomes in embryos. It can be useful in special cases, such as an advanced maternal age. Examples of aneuploid embryos include trisomy 18 and trisomy 21, also known as Edward and Down sindrome.


Answer from: Alessandra Parrella

Embryologist, Andrologist, Embriologist
IVF-Life Group

An euploid embryo is an embryo that has the correct number of chromosomes while an aneuploid embryo on the contrary has an incorrect number of chromosomes – this means that there is one chromosome more or one chromosome less, for example, and in this case, these embryos that are considered aneuploid they cannot be transferred because can lead to pregnancy loss.

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