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Why do PGT-A / PGS embryos fail?

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1 fertility expert(s) answered this question

Answer from: Dimitra Christopikou, Clinical Laboratory Geneticist

Geneticist, Head of the PGT lab Embryogenesis IVF Unit Athens
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This is a very good question with a blurry answer. Many people out there are trying to find the reason for this question, why euploid embryo’s, embryo’s that tend to have a nice pair of chromosomes are failing to implant or even sometimes miscarry. We don’t have an answer but one reason may be it is to do with other types of mechanisms involving embryo metabolisms or to do with mitochondrial DNA, whether we have high rates or lower rates of mitochondrial DNA or other factors unknown so far. This is something we are constantly looking at and what researchers are looking into right now.

About this question:

Why do euploid embryos fail?

Does genetic testing of embryos guarantee implantation? What information can give us genetic testing? Does the transfer of euploid embryos suggest problems in the endometrium area in case of implantation failure?

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