Answer from:
When we do genetic testing and we are looking for micro deletions in males who have no sperm, we can find out the different regions of micro deletion on Y chromosomes and the ZFC areas. So if we find that it affects a certain region, then we can know there is definitely no sperm that will be found even if we do the testing via testicular biopsy. At that point unfortunately, we will have to disclose or tell the patient that they will not be able to conceive using their own gametes. In the same cases with females, as I said with turner syndrome, it is extremely difficult and in that case, we have to progressively as we get older, as we know that the ovary loses the complete capability of any eggs. At that point we will have to disclose to the patient that they will not be able to have a child using their own gametes.
Answer from:
The thing is for a couple to be having regular, unprotected intercourse for at least 12 menstrual cycles or one year – in practical terms, before we consider a diagnosis of infertility, that’s what in the UK the National Institute of Health and Clinical Care Excellence NICE have said should we have diagnose infertility but there are also situations where there is something obviously not right. For instance, if someone is not having regular periods or no periods at all or is known to have severe endometriosis or the man is known to have a male factor problem, then you don’t need to wait the whole 12 months – you can make a diagnosis at pretty much any point.
