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How quickly does uterine lining thicken?

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2 fertility expert(s) answered this question

Answer from: Patricio Calamera, MD, MSc, ObGyn

Gynaecologist, Specialist in Reproductive Medicine Ginemed
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Well uterine lining can get thick really fast or it can take a little longer to get to the point in which we feel comfortable for an embryo transfer. That’s why we do ultrasounds to see when we get to that point in which we feel comfortable for an embryo transfer. While doing a cycle with medication, well, we give estrogens to the patient. I usually do the ultrasound on day 10 between day 10 and 12 of the day that they start with the medication and we see how thick the endometrium is at that moment. If it needs more time or more dose, we higher the dose and we give more time and we start monitoring till we get to the point in which we get the thicker endometrium that we need.

Answer from: Lyubov Mykhaylyshyn, MD, Phd

Gynaecologist, Head of IVF department Medical centre “Alternativa” for Human Reproduction Clinic “Alterntyva”
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Yes, the speed of the uterine line growth also depends on the follicular growth. They grow simultaneously, in natural cycle, just follicle appears dominant, so the endometrium start growing but the important question is in the programed cycle when we exclude the dominant follicular growing and by estrogens, so we doctors, we are often thinking about we can prescribe these estrogens and they are very nice studies published by Shankara, she showed us that if the duration of the follicular phase is up to 20 days, so it would not harm the implantation rate but if this duration will be longer, so afterwards, we will have probably lower level of implantation. Normally we have to reach the optimal sickness up to 20 days but usually it also have to be not shorter than for 8 days because if the duration of follicular phase is shorter than 8 days there is a higher risk of miscarriage. These data are also coming from other studies.

About this question:

How long does it take for uterine lining to thicken?

For women of reproductive age, the uterine lining thickens and thins according to their menstrual cycle. The endometrium can be anywhere from slightly less than 1 mm to even 16 mm in thickness. Studies suggest that uterine lining thickness under 6 mm results in problems with getting pregnant, even with IVF or egg donation. Therefore, most reproductive specialists would prefer their patients to have their lining of at least 7-8 mm. How to increase the uterine lining thickness, then?

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