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How common is genetic infertility?

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2 fertility expert(s) answered this question

Answer from: Malini Uppal, MBBS, DGO Diploma Prenatal Genetics and Foetal Medicine

Gynaecologist, Medical Director and PR to HFEA
GENNET City Fertility
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Again I would say with more awareness or research, whatever has been found, a lot of the male infertility that we see, 50% of it will be linked to some sort of genetic condition. So more of male infertility is linked to genetics and we see that quite often in our practice. Overall there are statistics out there that will say that if you have an infertile couple, looking at the general population, 7% of the couples will be infertile or have difficulty or infertility. Out of the 7% it is considered that 50% of them would have some sort of genetic link.

Answer from: Raj Mathur, MD

Gynaecologist, Chair of the British Fertility Society, Consultant at Manchester University NHS Foundation Trust
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Due to purely genetic causes is rare apart from very severe conditions like cystic fibrosis or Turner syndrome. The majority of cases where there is infertility don’t really have a genetic basis to that.

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How much of infertility is genetic?

Some genetic conditions are well known and described as the ones that cause infertility. Even a single gene defect can lead to some health conditions that can, in turn, cause problems with your fertility. Also, abnormal chromosomes can be a direct cause of male infertility.

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