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What is the difference between Ovarian Rejuvenation and Ovarian Rejuvenation with PRP?

1 fertility expert(s) answered this question

Answer from: Halyna Strelko, MD

Gynaecologist, Co-founder& Leading Reproduction Specialist
IVMED Fertility Center
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There are different types of rejuvenation. If we are talking about PRP, the method is to take blood, own blood, prepare this blood in a specific way, necessary centrifugate several times, take these activated lymphocytes and inject them inside of the ovary. We have done this procedure several times and in some cases, it improved after two-three months. In some cases, sincerely speaking I don’t see a lot of results. It is difficult to say in which case it will be really helpful.

We are doing that for thin endometrium: we inject these cells inside of the uterus during the preparation for the embryo transfer and sometimes it improves endometrium but in some patients there is no reaction (no improvement). There is another method of rejuvenation: we take some part of ovarian tissue, then do specific preparation to activate factors that normally regulate the transformation from preantral follicles in small antral, etc., then, we put it back. This method, according to the literature, gives better results. In Ukraine, we still did not try to do that. One clinic reported that tried to do it but not enough information if it is maybe very very helpful. Some authors say that it is a good and interesting method.

Just talking about it seems that there are two methods one: using activated lymphocytes after specific preparation, we inject them in the ovary and this is PRP therapy. It may be helpful. Some publications say that it is very very helpful. From my own experience, yes, in some cases it may be helpful but not in all cases work well. Another method is activating ovarian tissue with specific factors which normally regulate follicle recruitment and follicular atresia and this is the main difference

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Is there difference between PRP and ovarian rejuvenation with PRP?

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