Search

Can infertility be hereditary?

Category:
2 fertility expert(s) answered this question

Can infertility run in families?

Can infertility be genetic? Is it possible that infertility hereditary?

Answer from:
Gynaecologist, Medical Director and PR to HFEA GENNET City Fertility
play-video-icon-yt

Infertility is multifactorial. It has a lot of components, it is very complex, not a simple thing. But can it be inherited? Yes, it can. When we are taking a patients history, we always ask if there is anyone in the family who has gone through early menopause. We ask this because there could be a gene mutation and more links to gene mutations have now been found. This is what we believe can run into family and be transmitted. That is why if your mother has had early menopause, there is a likelihood tat you may also have early menopause and that means that this is inherited. Or there are genes now which we are seeing that are related to endometriosis. So if it has been in your family or your mother had severe endometriosis, it is likely that you carry that mutation or poly cystic ovaries. So now they are not classed as complete infertility, but as sub fertility or difficulty in getting pregnant and these can relate to things that run in the family. Simple things like fibroids which we know are linked in the family and are hereditary. If you have larger fibroids then again, that is linked in families, coming from ethnic backgrounds sometimes even. Some things may come and be more common in one ethnic background and can be a cause of infertility and of that gene pool.

Answer from:
Gynaecologist, Chair of the British Fertility Society, Consultant at Manchester University NHS Foundation Trust
play-video-icon-yt

Large no because to be hereditary means to be able to transmit it to your children and so on and if it’s a serious cause of infertility then obviously there’s great difficulty having children. So passing it on is also harder but having said that there are conditions that affect fertility that tend to run in families. So we know for instance that Polycystic Ovary Syndrome tends to run in families. Endometriosis is more common among women who have other female relatives with endometriosis. So these aren’t conditions that necessarily make you completely infertile but they can affect and do affect your fertility and reduce your fertility, make you require all sorts of treatment and yes they run in the family so your children may have a higher risk of developing them as well.

Find similar questions:

Related questions