Answer from: Patricio Calamera, MD, MSc, ObGyn
Let’s start with explaining that a mini IVF results from the idea of giving a low dose of medication in order to be the most physiological, to try to imitate what happens in every menstrual cycle if we don’t do anything, by that, this idea was trying to get the best quality oocytes by not forcing the ovary to produce and grow them. So, this is basically the main idea of mini IVF. Actually nowadays, we know that it depends on the quality of the oocytes and that is difficult. If you have a low ovarian reserve, you can do mild or regular IVF and still get bad quality oocytes – that’s something that depends on each woman and on each ovary, it’s not something that we can sort of divide through different types of approach in an IVF protocol.
Answer from: Malini Uppal, MBBS, DGO Diploma Prenatal Genetics and Foetal Medicine
At our fertility center, we do all types of treatment. So the success rate is based on the age group rather than the type of treatment we are doing. So what I can say is, again, the success rate will depend on which age group you fall into and what your ovarian reserve is. So most of the time mild IVF is performed for anyone over 40. So if you are between 40 and 42, the IVF cycle and success rate is around 20 to 25 percent. If you are in the age group of 42 to 44, then your success rate is around 15 percent. It is all age dependent, not the type of treatment, so your age depends on what the success rate will be.
What we can expect from mini IVF in terms of the IVF outcome?
Nowadays patients not only are concerned about costs of treatment but also about the effect of drugs used during the stimulation process. Studies confirmed that higher dosage is not necessarily as effective in case of patients with low or diminished ovarian. Similar case is with PCO patients. What and who can benefit from Mini IVF or Natural Cycle IVF?