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It helps us with selection of the embryos so, for example, we have the time lapse machine that has been used for a few years now already and has proven to help the embryologists make the right choice of the embryos that they would suggest for transfer or select for transfer. We’ll see more and more AI coming into play a big role in many fields of the medical area and therefore, embryology is also one part that is seeing AI being able to help with the selection. We have seen and reported in many clinics across the world that when they have used time lapse machine, for example, which is almost like a CCTV camera, watching the embryos continuously, it actually has helped increase the implantation rate and clinical pregnancy rate because better embryos have been selected through using the time-lapse machine.
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When we do an egg donation cycle, we have those beautiful embryo’s and which embryo to choose for the embryo transfer depends on which country and clinic you choose to work with. I think that outside of the US, most countries may not test the embryo’s with the technology of PGT (known as PGS) and there are different reasons why they don’t. In those countries we see more AI artificial intelligence helping in embryo selection. You also have real time microscopes that monitor the embryo’s development so there are a lot of advanced technologies that try to detect the best embryo. I think in a lot of places in the US, definitely in my practice we test the embryos , we make it very easy so that we know the genetics of the embryo whether it is normal or abnormal and once we know that within the normal embryo’s we look at embryo grading. With embryo grading, we grade them based on how they look and the can be graded A,B,C and D. Embryo grading has only to do with what are the chances of this embryo, how strong it is to implant because many people worry about how would you put a C embryo in and the child will be a C child, meaning there may be all kinds of health issues. It’s intuitive as I’d be afraid to tell someone we are not using a good quality embryo but I would want a good quality embryo.
It is a very natural and scary question, the reality is that the embryo quality has nothing to do with the pregnancy or the health of the baby. It is like having two plans and one plan has more than the other and may have more room to implant but the grading system just gives us an idea of what is the strength of the embryo for the first two weeks. Once the embryo is implanted, after those two weeks, the embryo whether it started as a C or D makes absolutely no difference because at that point they are all equal. But the grading system definitely helps us e.g. embryo’s with the grade A of B have a success rate of 70 to 80 percent, embryo’s with grade C maybe 60 to 65 and with a grade D, much lower than that. The second part we look at is how long it took for the embryo to make it to this final stage and we call them blast embryo’s. It may take this embryo 5,6 or 7 days and the shorter the time, the stronger the embryo. I think in our practice, as well as many others on the West coast, since we do test them, we look at what is normal and what is not normal and then we start to look at what is the grading, the date and so on and that is guaranteed. But outside of the US, you’d have AI, artificial technology, microscopes and so on, in real time to choose the best embryo.
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Artificial intelligence (AI) can nowadays be found in the IVF lab, for example in time-lapse incubators, the automation of sperm analysis, measuring sperm motility, or measuring facial resemblance for donor selection. These new technologies can help doctors and embryologists and provide them with security, efficiency, and productivity in the IVF lab and during consultations.
For example, Fenomatch is based on AI and measures facial resemblance. It is a tool specifically designed for fertility and it helps doctors and embryologists to select the right donor for the patient. This way, the decision on choosing the right donor is based on scientific arguments and gives peace of mind to the patient involved in the treatment.
